Abraham Fisher Selected Research

Muscarinic M1 Receptor

1/2022	Reimagining cholinergic therapy for Alzheimer's disease.
1/2012	Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease.
1/2008	M1 muscarinic agonists target major hallmarks of Alzheimer's disease--the pivotal role of brain M1 receptors.
12/2007	M1 muscarinic agonists target major hallmarks of Alzheimer's disease--an update.
1/2003	M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy.
8/2002	AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.

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Abraham Fisher Research Topics

Disease

11	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 08/2002
6	Cognitive Dysfunction 03/2013 - 08/2002
2	Neuroinflammatory Diseases 01/2018 - 01/2016
1	Disease Progression 01/2022
1	Dementia (Dementias) 01/2012
1	Parkinson Disease (Parkinson's Disease) 01/2003
1	Sjogren's Syndrome (Sjogren Syndrome) 08/2002

Drug/Important Bio-Agent (IBA)

9	Cholinergic Agents (Cholinergics)IBA 01/2022 - 08/2002
6	Muscarinic M1 ReceptorIBA 01/2022 - 08/2002
6	Muscarinic AgonistsIBA 07/2008 - 08/2002
4	Amyloid (Amyloid Fibrils)IBA 01/2018 - 08/2002
4	(S)- 2- ethyl- 8- methyl- 1- thia- 4,8- diazaspiro(4.5)decan- 3- oneIBA 01/2008 - 08/2002
4	Amyloid beta-PeptidesIBA 12/2007 - 08/2002
3	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022 - 07/2008
3	Rivastigmine (Exelon)FDA LinkGeneric 07/2008 - 08/2002
2	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2022 - 04/2009
2	Nerve Growth Factor (NGF)IBA 01/2022 - 08/2002
2	Proteins (Proteins, Gene)FDA Link 01/2012 - 08/2002
2	cevimeline (Evoxac)FDA Link 01/2008 - 08/2002
2	Nicotine FDA Link 01/2003 - 08/2002
1	Cholinesterases (Cholinesterase)IBA 01/2015
1	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2009
1	Donepezil (Aricept)FDA LinkGeneric 07/2008
1	Tacrine (Cognex)FDA Link 07/2008
1	Memantine (Namenda)FDA Link 07/2008
1	N-Methylaspartate (NMDA)IBA 07/2008
1	Galantamine (Galanthamine)FDA LinkGeneric 07/2008
1	Nootropic Agents (Nootropics)IBA 01/2008
1	Muscarinic AntagonistsIBA 01/2003
1	Peptides (Polypeptides)IBA 01/2003
1	Nerve Growth Factors (Neurotrophins)IBA 08/2002
1	Epidermal Growth Factor (EGF)IBA 08/2002

Therapy/Procedure

3	Therapeutics 01/2022 - 01/2003
1	Investigational Therapies (Experimental Therapy) 08/2002